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Illustration of RNA and RNA-targeted medicines alongside protein shapes, with one gray protein among yellow proteins

Innovation at Work

Pioneering RNA-Targeted Medicines: What They Are and Why They Matter

RNA-targeted medicines work differently. Learn how they interact with RNA to address disease earlier than traditional approaches – and why it matters.

People & Impact

Ionis Ranked #1 Top Employer by Science

Ionis has been recognized as Science’s #1 Top Employer for 2026. In only our second year of eligibility, this honor highlights our industry-leading innovation, talented employees and strong values-based culture.

Patient Voices

Finding Joy in the Journey: David and Melissa’s Life with Alexander disease (AxD)

For David and his mother, Melissa, moments of joy are an important part of life with Alexander disease (AxD), an ultra-rare, progressive and often fatal neurological disorder that affects approximately 1 in 1 to 3 million people worldwide.

Son in a wheelchair walking down a sidewalk past a stop sign with his mom/caregiver

People & Impact

Ionis’ CFO Beth Hougen Named 2026 CFO of the Year by San Diego Business Journal

Beth’s recognition reflects more than 25 years of leadership at Ionis. As a member of the executive leadership team, she has helped guide the company’s transformation from an organization focused primarily on research and early development into a fully integrated commercial-stage biotech.