Newsroom Articles

For David and his mother, Melissa, moments of joy are an important part of life with Alexander disease (AxD), an ultra-rare, progressive and often fatal neurological disorder that affects approximately 1 in 1 to 3 million people worldwide.

Through their stories, families, advocates and experts paint a vivid picture of what life with Angelman syndrome looks like – the obstacles, the triumphs and the moments of strength that define their journeys. They share their experiences navigating the path to diagnosis, the hallmark signs and symptoms of AS and, most importantly, the incredible joy that their children with AS bring to their lives. 

Recognizing our industry-leading scientific innovation and company culture, Science magazine ranked Ionis their #2 Top Employer in 2025.

Championing an investigational medicine to make a meaningful difference in the lives of those living with HAE

Ionis is proud to announce that we have ranked #6 on the San Diego Business Journal’s 2025 Best Places to Work list in the Large Companies category. This marks our second consecutive year being recognized and our first year breaking into the Top 10…